1. Human genome project (HGP) identified approximately ______________ number of genes in the human genome.

A. 20,000 - 30,000

B. 1,00,000

C. 2,000 - 3,000

D. 80,000 - 1, 40,000

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2. DNA and RNA differ by:

A. Nitrigen bases and sugars

B. Nitrogen bases and phosphate groups

C. Number of C-atoms in sugars

D. Sugar and phosphate groups

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3. Translation is synthesis of

A. DNA over DNA

B. RNA over DNA

C. DNA over RNA

D. Protein over RNA

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4. Termination codon is:

A. UGG

B. GUG

C. UAG

D. AUG

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5. Who first proposed that DNA is genetic material?

A. Griffith

B. Watson and Crick

C. Hershey and Chase

D. Nirenberg

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6. In a gene mutation, adenine is replaced by guanine. It is

A. Frame-shift mutation

B. Transcription

C. Transition

D. Transversion

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7. Nucleosome contains

A. Histone molecules

B. Nucleotides

C. Nucleoplasmin

D. Nuclear pore complex

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8. DNA element with ability to change position is

A. Cistron

B. Intron

C. Recon

D. Transposon

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9. Which of the following causes cancer?

A. Activation of oncogenes

B. Inactivation of tumor supressor genes

C. Proto-oncogenes

D. Both A and B

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10. Which of the following statement about transciption is FALSE?

A. It is the synthesis of RNA from DNA

B. Transciption continues throughout the life of a cell

C. It produces single strand of RNA

D. It produces double strand of DNA

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